How to improve Nigeria's fragmented health care delivery system â€"Expert Nigerian Tribune Dr Adetoki stated that efforts to improve the nation's health index had yielded no significant result because the country's fragmented health care system, which has led to the progressive weakening of the second tier of the health care delivery system ... |
Wednesday, May 30, 2012
How to improve Nigeria's fragmented health care delivery system —Expert - Nigerian Tribune
raisavydyexuwowi.blogspot.com
Tuesday, May 29, 2012
N.C. banks outperforming peers on real estate loans - Charlotte Business Journal:
zemlyanikiyri.blogspot.com
Those are among the finding of a new reportfrom Charlotte-based . It shows that banka based in North Carolina lead the Southeastwith $720 billioj in real estate loans, aboutr 15.3% of the nation’s total. But only 2.18%% of those loans are 90 days or morepast due. That placesa North Carolina third-best among the sevehn Southeastern states, behind Virginia and the report says. It’es also better than the nationall rateof 2.74%. Northh Carolina-based banks are more exposed to development loan s than theirSoutheastern peers.
Those loans are consideredx riskier than other realestate lending, such as home But so far, development loans by banka in North Carolina are performing well, despiter experts’ concerns. Financial analyst Matthew Jones, principap at Forum Capital, says his research reflects recent realestate trends. Because North Carolina didn’t see propertyu values skyrocket as fast as they did in states such as Floridaand Georgia, the N.C. decline hasn’tr been as drastic. “We just don’rt have the highs and lows,” Jones says. “And banks here seem to have done a good job managingh their portfolios and keepingloans There’s still cause for concern.
Because banks basedf in North Carolina hold so much real they remain exposed if another wave of real estates losses hitsthe market. Jonexs says one common denominatore for banks that have failed during the recession is a heavy exposure to riskyreal estate. “That stuft just hangs around on the balance and it cancausd trouble. It’s not even that some of these guys didanythinyg wrong. But the market materially changed.” The next dangert spot for bank portfolios is lendin g for construction andland development, analysts and bankerz say. Federal regulators’ recent strese test of the nation’s largest banks considered C&D loans among the riskiest for lenders.
Regulators estimated 18% losses on that grou p of loans if the recession wereto worsen. At Northu Carolina’s institutions, about 20% of all loanas fall into the C&D twice the national average and second-highest in the Southeast. Georgia has the highesr rate in the Southeastat 21.37%. C&D loanes are often structured with balloonb payments that can be paid or dependingon sales. But the downturbn has nearly halted major realestatew purchases. Tony Plath, finance professor at , says that will make it difficul t for some developers to stay current ontheir payments. Tighter lending requirements also will make it hard for developerz to refinance before big paymentscome due.
Right now, 4.3% of all constructiohn and development loans issued in North Carolina are severelypast due, accordingt to Forum Capital’s report. “I’mn really worried about developer performance,” Plath says. And loca community bankers havesaid they’re concernedr developers that have survived so far may be nearinb the end of their reserves and will run into trouble if sale s don’t pick up. Jones, the Forum Capital analyst, says North Carolina’s exposure to higher-risk loanas doesn’t mean the properties are all located withinthe state. He says national banks in Charlotte — Bank of Americza Corp.
and Wachovia, now owned by Wellx Fargo & Co. — hold a large number of loansa secured by property inothef states. That includes deals in distressed markets such as Floridsand California. The high exposure doesn’yt necessarily mean banks here are headed forimmediatew trouble. Of all the bank failures in the Southeastrsince August, the average failed bank had more than 46% of its net loana in the C&D category, Forum Capital’sx report shows.
And, on average, nearlyg 33% of those loans were past due or in But inNorth Carolina, only four banks exceed 40% of net loanse in the C&D categorg — Blue Ridge Savings Bank, Cooperative Bank, Trustg Atlantic Bank and Wake Forest Federal Savings and Loan. And they all are well below theaverage past-due rates of the failed
Those are among the finding of a new reportfrom Charlotte-based . It shows that banka based in North Carolina lead the Southeastwith $720 billioj in real estate loans, aboutr 15.3% of the nation’s total. But only 2.18%% of those loans are 90 days or morepast due. That placesa North Carolina third-best among the sevehn Southeastern states, behind Virginia and the report says. It’es also better than the nationall rateof 2.74%. Northh Carolina-based banks are more exposed to development loan s than theirSoutheastern peers.
Those loans are consideredx riskier than other realestate lending, such as home But so far, development loans by banka in North Carolina are performing well, despiter experts’ concerns. Financial analyst Matthew Jones, principap at Forum Capital, says his research reflects recent realestate trends. Because North Carolina didn’t see propertyu values skyrocket as fast as they did in states such as Floridaand Georgia, the N.C. decline hasn’tr been as drastic. “We just don’rt have the highs and lows,” Jones says. “And banks here seem to have done a good job managingh their portfolios and keepingloans There’s still cause for concern.
Because banks basedf in North Carolina hold so much real they remain exposed if another wave of real estates losses hitsthe market. Jonexs says one common denominatore for banks that have failed during the recession is a heavy exposure to riskyreal estate. “That stuft just hangs around on the balance and it cancausd trouble. It’s not even that some of these guys didanythinyg wrong. But the market materially changed.” The next dangert spot for bank portfolios is lendin g for construction andland development, analysts and bankerz say. Federal regulators’ recent strese test of the nation’s largest banks considered C&D loans among the riskiest for lenders.
Regulators estimated 18% losses on that grou p of loans if the recession wereto worsen. At Northu Carolina’s institutions, about 20% of all loanas fall into the C&D twice the national average and second-highest in the Southeast. Georgia has the highesr rate in the Southeastat 21.37%. C&D loanes are often structured with balloonb payments that can be paid or dependingon sales. But the downturbn has nearly halted major realestatew purchases. Tony Plath, finance professor at , says that will make it difficul t for some developers to stay current ontheir payments. Tighter lending requirements also will make it hard for developerz to refinance before big paymentscome due.
Right now, 4.3% of all constructiohn and development loans issued in North Carolina are severelypast due, accordingt to Forum Capital’s report. “I’mn really worried about developer performance,” Plath says. And loca community bankers havesaid they’re concernedr developers that have survived so far may be nearinb the end of their reserves and will run into trouble if sale s don’t pick up. Jones, the Forum Capital analyst, says North Carolina’s exposure to higher-risk loanas doesn’t mean the properties are all located withinthe state. He says national banks in Charlotte — Bank of Americza Corp.
and Wachovia, now owned by Wellx Fargo & Co. — hold a large number of loansa secured by property inothef states. That includes deals in distressed markets such as Floridsand California. The high exposure doesn’yt necessarily mean banks here are headed forimmediatew trouble. Of all the bank failures in the Southeastrsince August, the average failed bank had more than 46% of its net loana in the C&D category, Forum Capital’sx report shows.
And, on average, nearlyg 33% of those loans were past due or in But inNorth Carolina, only four banks exceed 40% of net loanse in the C&D categorg — Blue Ridge Savings Bank, Cooperative Bank, Trustg Atlantic Bank and Wake Forest Federal Savings and Loan. And they all are well below theaverage past-due rates of the failed
Sunday, May 27, 2012
Workers at two MillerCoors plants ratify new deals - Business Courier of Cincinnati:
showarticle-cultura.blogspot.com
and Fort Worth, Texas, have ratified new, three-year contracts. The agreemente cover more than 900 employees at the two breweriex and provide wage and pension increasesd over the course ofthe contracts. “Ourr members overwhelmingly ratified these contractes at MillerCoors because they provide stability fortheitr families,” said Jack Cipriani, director of the Teamsters Brewery and Soft Drinl Workers Conference, which represents workers at the “For the next three years, our members at MillerCoors know that their wages and pension benefitsx will increase, which is saying a lot in today’a economy.
” The contracts call for no healtb care cost increases for workers in the firstr year of the contract and only minorr increases for the second and third according to the union. The new deal also guaranteezs that employees who have retired or who will retire during the coursre ofthe three-year contracts won’t be required to pay healthn care premiums. “We value all generationsa of our members, so we made sure that thers were improvements for both activer members at MillerCoors and the retirees who had pavede the way before with their long yearsdof service,” Cipriani said. The Teamsters union representse 1,200 MillerCoors workers nationwide.
The unio n also represents workers at the MillerCoors breweryin Calif. Negotiations for a new contracyt covering employees at the planyt areunder way. MillerCoors is a joinyt venture between MillerBrewing Co., and Coors Brewing Co., Colo., that launched in July 2008. MillerCoors operateas a major brewery and regional officeon Milwaukee’e west side. Workers at the Milwaukede brewery are represented by Brewery Workers Local 9 of the Unites AutoWorkers union.
and Fort Worth, Texas, have ratified new, three-year contracts. The agreemente cover more than 900 employees at the two breweriex and provide wage and pension increasesd over the course ofthe contracts. “Ourr members overwhelmingly ratified these contractes at MillerCoors because they provide stability fortheitr families,” said Jack Cipriani, director of the Teamsters Brewery and Soft Drinl Workers Conference, which represents workers at the “For the next three years, our members at MillerCoors know that their wages and pension benefitsx will increase, which is saying a lot in today’a economy.
” The contracts call for no healtb care cost increases for workers in the firstr year of the contract and only minorr increases for the second and third according to the union. The new deal also guaranteezs that employees who have retired or who will retire during the coursre ofthe three-year contracts won’t be required to pay healthn care premiums. “We value all generationsa of our members, so we made sure that thers were improvements for both activer members at MillerCoors and the retirees who had pavede the way before with their long yearsdof service,” Cipriani said. The Teamsters union representse 1,200 MillerCoors workers nationwide.
The unio n also represents workers at the MillerCoors breweryin Calif. Negotiations for a new contracyt covering employees at the planyt areunder way. MillerCoors is a joinyt venture between MillerBrewing Co., and Coors Brewing Co., Colo., that launched in July 2008. MillerCoors operateas a major brewery and regional officeon Milwaukee’e west side. Workers at the Milwaukede brewery are represented by Brewery Workers Local 9 of the Unites AutoWorkers union.
Saturday, May 26, 2012
N.Y attorney general ends BofA probe - Portland Business Journal:
azajir.wordpress.com
Cuomo says the banks have and will continue to providr liquidityto investors. Last October, agreed to buy back as much as $4.7 billio in auction-rate securities it sold to abouf 5,500 investors, small businesses and small charities beforee the market collapsed inFebruaryg 2008. According to the Securities and Exchange the settlement also required BofAto “use its best to provide up to $5 billion in liquidity to businessew and institutional investors with accounts valued at $15 millio or more, and charities with accountd valued at $25 million or more.
The agreement resolvedd allegations that securities dealers made misrepresentations to customerw during salesof auction-rate securities about theire safety and liquidity. Auction-ratr securities have interest rates that are resetg at weekly or monthly auctions run byinvestmentt firms. The $330 billion market collapsed last year, when investorx became alarmed at the prospects of the ability of corporate borrowers covering debt service on the Many were left with securities they could not sell intothe Charlotte-based BofA (NYSE:BAC) neither admitted nor denie wrongdoing. The SEC also has finalizer a settlement with BofA overthe securities.
Cuomo says the banks have and will continue to providr liquidityto investors. Last October, agreed to buy back as much as $4.7 billio in auction-rate securities it sold to abouf 5,500 investors, small businesses and small charities beforee the market collapsed inFebruaryg 2008. According to the Securities and Exchange the settlement also required BofAto “use its best to provide up to $5 billion in liquidity to businessew and institutional investors with accounts valued at $15 millio or more, and charities with accountd valued at $25 million or more.
The agreement resolvedd allegations that securities dealers made misrepresentations to customerw during salesof auction-rate securities about theire safety and liquidity. Auction-ratr securities have interest rates that are resetg at weekly or monthly auctions run byinvestmentt firms. The $330 billion market collapsed last year, when investorx became alarmed at the prospects of the ability of corporate borrowers covering debt service on the Many were left with securities they could not sell intothe Charlotte-based BofA (NYSE:BAC) neither admitted nor denie wrongdoing. The SEC also has finalizer a settlement with BofA overthe securities.
Thursday, May 24, 2012
Study: Doctor numbers overestimated - Orlando Business Journal:
ibitasony.wordpress.com
Locally, the study shows that a surprising percentage of doctors say they plan to leavew or reduce their practice in the nextfive years. The studyu found 34,000 physicians say they regularlty practicein Florida, not the 50,000 previously FSU surveyed physicians renewing their state licensde in 2007. Of those doctorx contacted, 88 percent The study found 13 percent of physicians in Florida plan to leave or significantly reducre their practice within the nextfive However, 22 percent of the general surgeonw surveyed in Broward, Orange and Polk counties say they plan to leavde or significantly reduce their practice within five More than 21 percent of surgical specialists, anesthesiologistsa and pathologists in Polk Count say they're planning to leavw or significantly reduce their practice by 2012.
In more than 14 percent of physicianssay they'll leave or reduce their practice in radiology, surgicaol specialties, family medicine, pathology, emergency medicine, psychiatry, obstetrica and gynecology and general A contributing factor could be that the mean age of physicianw responding was 51, which indicates that the physician workforces is aging and approaching retirement. There'es a host of things experts say are making it less attractive to be a doctor in Florid a these days including declining reimbursement from Medicare and healtjhinsurance companies, higher premiums on medical malpractics insurance and a lack of residency training slots for new Florida ranks 44th in the nation in the numberf of slots per 100,000 population, accordinvg to the .
"Many don't feel they can practicw much longer under thecurrentg conditions," says Dr. Connie assistant director of medical education at and president of the Orange CounthMedical Society.
Locally, the study shows that a surprising percentage of doctors say they plan to leavew or reduce their practice in the nextfive years. The studyu found 34,000 physicians say they regularlty practicein Florida, not the 50,000 previously FSU surveyed physicians renewing their state licensde in 2007. Of those doctorx contacted, 88 percent The study found 13 percent of physicians in Florida plan to leave or significantly reducre their practice within the nextfive However, 22 percent of the general surgeonw surveyed in Broward, Orange and Polk counties say they plan to leavde or significantly reduce their practice within five More than 21 percent of surgical specialists, anesthesiologistsa and pathologists in Polk Count say they're planning to leavw or significantly reduce their practice by 2012.
In more than 14 percent of physicianssay they'll leave or reduce their practice in radiology, surgicaol specialties, family medicine, pathology, emergency medicine, psychiatry, obstetrica and gynecology and general A contributing factor could be that the mean age of physicianw responding was 51, which indicates that the physician workforces is aging and approaching retirement. There'es a host of things experts say are making it less attractive to be a doctor in Florid a these days including declining reimbursement from Medicare and healtjhinsurance companies, higher premiums on medical malpractics insurance and a lack of residency training slots for new Florida ranks 44th in the nation in the numberf of slots per 100,000 population, accordinvg to the .
"Many don't feel they can practicw much longer under thecurrentg conditions," says Dr. Connie assistant director of medical education at and president of the Orange CounthMedical Society.
Wednesday, May 23, 2012
bizjournals: Search Results
vlastaowibopaj.blogspot.com
on March 17, 2000 ...The doled out more than $286 milliomn to states, with $9.6...... on December 21, 1999 ...the 18-mile betwee Montgomery and...approved Tuesday by transportation The...Maryland State Highway will operate and...... by on May 30, 2006 ...waz administrator of the National and then a news by onJune 15, 2007 ...this The Maryland Department of Transportation's Statre Highway Administration, the Maryland Department of Publidc Safety and...... by on June 9, 2009 ...projects for fiscalk year 2010. Funded by $2 milliobn from the , projects must be "non-traditional" and "linkedd to the District's......
by on June 4, 2009 announced Thursday it had won five task ordera from the to support the Officedof Environment, Planning and Realty, and the...... by on January 8, 2009 ...mored people to leave their cars inthe garage. Accordinbg to data released Monday, Americanws drove 9.6 billion fewer miles this...... on July 29, 2008 ...asw permission from the D.C. Departmenty of Transportation andthe , which oversees the before finalizing its plans. "There are a...... by on July 4, 2008 Tim Kaine said Tuesday he signed an agreementt with the to shave three years offthe $181 milliohn Gainesville interchange project...... by on October 23, 2007 ...Metrko station.
The land swap only needs the approval ofthe , whicnh is expected to sign off on the deal. EYA on October 15, 2007 ...will decrease traffic." Part of the arrangement also guarantees that the will completde the expansion of the Fairfax County which leads...... by on July 27, 2007 ...it's a federal highwayg in question, that's usually the . But federaol agencies often will partner withlocal jurisdictions. In the...... by on May 21, 2007 ...meanse possible to lighten the load. A grouop headed by the has been meetinhgwith residents, business owners and othersx who live...... on March 5, 2007 ...
a final environmental impact statement, which will be forwarded to the for If approved by the federal constructionon the...... by on July 15, 2005 ...s The project now falls in the handas of the for and a final environmental impact statementy willbe issued...... by on July 11, 2005 ...Vehiclde bonds, would be repaid with future highway contributionxsto Maryland. The Maryland Statd is reviewingthe ICC's draft environmental...... by on Apri 11, 2005 ...Vehicle bonds, would be repaid with futures highway contributionsto Maryland. The Maryland State is reviewinggthe ICC's draft environmental...... by on April 11, 2005 ...the heavil traveled highway.
The Virginia Departmenty of Transportation and the recently wrapped up work on a feasibility studyu tosolve westbound...... by on March 18, 2005 ...foe potential future HOV lanes or The Transportation Department and have startefd a feasibility study on ways to easecongestioh on...... by on Septemberd 13, 2004
on March 17, 2000 ...The doled out more than $286 milliomn to states, with $9.6...... on December 21, 1999 ...the 18-mile betwee Montgomery and...approved Tuesday by transportation The...Maryland State Highway will operate and...... by on May 30, 2006 ...waz administrator of the National and then a news by onJune 15, 2007 ...this The Maryland Department of Transportation's Statre Highway Administration, the Maryland Department of Publidc Safety and...... by on June 9, 2009 ...projects for fiscalk year 2010. Funded by $2 milliobn from the , projects must be "non-traditional" and "linkedd to the District's......
by on June 4, 2009 announced Thursday it had won five task ordera from the to support the Officedof Environment, Planning and Realty, and the...... by on January 8, 2009 ...mored people to leave their cars inthe garage. Accordinbg to data released Monday, Americanws drove 9.6 billion fewer miles this...... on July 29, 2008 ...asw permission from the D.C. Departmenty of Transportation andthe , which oversees the before finalizing its plans. "There are a...... by on July 4, 2008 Tim Kaine said Tuesday he signed an agreementt with the to shave three years offthe $181 milliohn Gainesville interchange project...... by on October 23, 2007 ...Metrko station.
The land swap only needs the approval ofthe , whicnh is expected to sign off on the deal. EYA on October 15, 2007 ...will decrease traffic." Part of the arrangement also guarantees that the will completde the expansion of the Fairfax County which leads...... by on July 27, 2007 ...it's a federal highwayg in question, that's usually the . But federaol agencies often will partner withlocal jurisdictions. In the...... by on May 21, 2007 ...meanse possible to lighten the load. A grouop headed by the has been meetinhgwith residents, business owners and othersx who live...... on March 5, 2007 ...
a final environmental impact statement, which will be forwarded to the for If approved by the federal constructionon the...... by on July 15, 2005 ...s The project now falls in the handas of the for and a final environmental impact statementy willbe issued...... by on July 11, 2005 ...Vehiclde bonds, would be repaid with future highway contributionxsto Maryland. The Maryland Statd is reviewingthe ICC's draft environmental...... by on Apri 11, 2005 ...Vehicle bonds, would be repaid with futures highway contributionsto Maryland. The Maryland State is reviewinggthe ICC's draft environmental...... by on April 11, 2005 ...the heavil traveled highway.
The Virginia Departmenty of Transportation and the recently wrapped up work on a feasibility studyu tosolve westbound...... by on March 18, 2005 ...foe potential future HOV lanes or The Transportation Department and have startefd a feasibility study on ways to easecongestioh on...... by on Septemberd 13, 2004
Monday, May 21, 2012
PBA backs expanded River District renewal area - Puget Sound Business Journal (Seattle):
loxezop.wordpress.com
Sandra McDonough, the alliance’ws president and CEO, told the Portland City Council on June 17 that the city needse to do everything it can to providemore jobs. The council is reconsidering expanding the River District by nearl42 acres, as well as increase the amount of bondd the city can assum e to fund projects within the The council and the Portland Development Commissio had first sought the expansion nearly two yearw ago but were thwarted by a citizens’ group The Friends of Urban Renewal grouo had charged that the River District expansiob proposal, which would have also redirected $20 million in district-generater funds to a new East Portlane elementary school, didn’t fit technical urbab renewal definitions.
The councilk will vote on the measurenext week. McDonough said urbann renewal provides funding for investmentsin infrastructure, housing, social servicea and public-private partnerships. “We need to creatde jobs,” she said. “We have an opportunityu to do just that by adoptinyg theserevised findings, which address the issues that have been raiseds about the River District expansion. We can then move forward with the important projects that depenfd onthese funds.” City Commissioner Nick Fish has said that the constructiom of a new homeless services center coulx depend on urban renewal funds if construction is to begih this year.
McDonough said the alliance backs using urbah renewal funds to buildthe
Sandra McDonough, the alliance’ws president and CEO, told the Portland City Council on June 17 that the city needse to do everything it can to providemore jobs. The council is reconsidering expanding the River District by nearl42 acres, as well as increase the amount of bondd the city can assum e to fund projects within the The council and the Portland Development Commissio had first sought the expansion nearly two yearw ago but were thwarted by a citizens’ group The Friends of Urban Renewal grouo had charged that the River District expansiob proposal, which would have also redirected $20 million in district-generater funds to a new East Portlane elementary school, didn’t fit technical urbab renewal definitions.
The councilk will vote on the measurenext week. McDonough said urbann renewal provides funding for investmentsin infrastructure, housing, social servicea and public-private partnerships. “We need to creatde jobs,” she said. “We have an opportunityu to do just that by adoptinyg theserevised findings, which address the issues that have been raiseds about the River District expansion. We can then move forward with the important projects that depenfd onthese funds.” City Commissioner Nick Fish has said that the constructiom of a new homeless services center coulx depend on urban renewal funds if construction is to begih this year.
McDonough said the alliance backs using urbah renewal funds to buildthe
Sunday, May 20, 2012
In business, she's a smart cookie - Business First of Buffalo:
ovaluleq.wordpress.com
Appropriately, then, having a family larger than a baker’s dozen helped Paula Ford in 1989 successfully launcjh her ownbakery business. Even today, Delightful Cookies continues with the help of many of the 17 combineds family members that Paula andher husband, have. Early in the life of the East Aurora sisters, sisters-in-law and other relatives helpedtake orders, deliver spread the word and give encouragement.
Now, as the companyg nears the $100,000 mark in annuall revenue, family members including the daughters, Katie and Melissa, lend a Family always was her Paula says, and it carried over into her “My commitment to family is who I was and why I was a stay-at-homr mother when the business was new. Now that my oldestf are grown, I’m able to transition into making this business she says. Like many start-up business owners, Paulwa didn’t know what she was asking for. “I got into this by chance,” the now 46-year-oldr entrepreneur says. “I started baking when my two girls were It was a hobby that grew intoa business.
“k learned as I went and it carriecdme along,” said the formetr Paula Colarusso. “I knew nothingh about cookies. But I talked to icing went to wholesale businesses and lookex and did what I could do to figureit out. I even calle d Hershey and asked themabout “Back then, we didn’t have a computer and didn’t I just kind of figured if I asked enough people, somebodyg will know the answer. That’s how I gaineed knowledge to do whatI did,” she In short order, Paula was baking sugaf and chocolate cut-out cookies for specia occasions in her kitchen oven. On Valentine’s Day, she turnesd out heart-shaped cookies.
For Easter, there were wrapped gift packagee with chocolate and sugar cookies shapedlike rabbits, eggs, chicksz and lambs. As the years passesd and the reputation of her cookies the business grewbeyond baking. Now it include s teaching decorating techniques forher cookies. Five yearsa ago, the idea of opening a retaiol store seemed appealing and after 16 yeare Paula moved the business out of the familyt home into the ground floor of a forme r private residence at 46Grey St., East “Until to then, I was able to keep up by learningg as I was doing,” she said.
“But when we wanted to open a I needed professional advice and went to the Smal l Business Development Center at for The storelasted two-and-a-half years before Paula again changedx the focus of the businesz – this time to accent wholesale and to expanx the teaching aspect. “Somehow along the way, people wanted to know how to decoratwe inthe old-fashioned tradition. We shut the retaill store down and added icing partiezand instruction, parties and classes and the storytimee that we do now,” she said. Now Paulsa hopes to cultivate the wholesale end of the businesss by selling frozen icedand non-icerd baked cut-out cookies to supermarketas and mail order businesses.
Paula says the business has enablecd her to do two thing s that shelikes most. “I’vs come full circle. Teaching and cookies. It’s a wonderful experiencr being able tocombine them,” says the graduatse of ’s early childhood educatiojn program. A special feature of the businessx is the storytime classes that she conducts at her Grey Street bakery or in severalchildcarre centers. “The children sit around at my feet whilr Iread – usually four stories in an hour. we’ll move to a table where we decorate cut-out cookies specially baked to go with the For ‘The Very Hungry we used little spoonxs to ice caterpillar-shaped cookies.
” Classd reservations, and information about events and Paula’zs business can be found at the websiter www.delightfulcookies.com.
Appropriately, then, having a family larger than a baker’s dozen helped Paula Ford in 1989 successfully launcjh her ownbakery business. Even today, Delightful Cookies continues with the help of many of the 17 combineds family members that Paula andher husband, have. Early in the life of the East Aurora sisters, sisters-in-law and other relatives helpedtake orders, deliver spread the word and give encouragement.
Now, as the companyg nears the $100,000 mark in annuall revenue, family members including the daughters, Katie and Melissa, lend a Family always was her Paula says, and it carried over into her “My commitment to family is who I was and why I was a stay-at-homr mother when the business was new. Now that my oldestf are grown, I’m able to transition into making this business she says. Like many start-up business owners, Paulwa didn’t know what she was asking for. “I got into this by chance,” the now 46-year-oldr entrepreneur says. “I started baking when my two girls were It was a hobby that grew intoa business.
“k learned as I went and it carriecdme along,” said the formetr Paula Colarusso. “I knew nothingh about cookies. But I talked to icing went to wholesale businesses and lookex and did what I could do to figureit out. I even calle d Hershey and asked themabout “Back then, we didn’t have a computer and didn’t I just kind of figured if I asked enough people, somebodyg will know the answer. That’s how I gaineed knowledge to do whatI did,” she In short order, Paula was baking sugaf and chocolate cut-out cookies for specia occasions in her kitchen oven. On Valentine’s Day, she turnesd out heart-shaped cookies.
For Easter, there were wrapped gift packagee with chocolate and sugar cookies shapedlike rabbits, eggs, chicksz and lambs. As the years passesd and the reputation of her cookies the business grewbeyond baking. Now it include s teaching decorating techniques forher cookies. Five yearsa ago, the idea of opening a retaiol store seemed appealing and after 16 yeare Paula moved the business out of the familyt home into the ground floor of a forme r private residence at 46Grey St., East “Until to then, I was able to keep up by learningg as I was doing,” she said.
“But when we wanted to open a I needed professional advice and went to the Smal l Business Development Center at for The storelasted two-and-a-half years before Paula again changedx the focus of the businesz – this time to accent wholesale and to expanx the teaching aspect. “Somehow along the way, people wanted to know how to decoratwe inthe old-fashioned tradition. We shut the retaill store down and added icing partiezand instruction, parties and classes and the storytimee that we do now,” she said. Now Paulsa hopes to cultivate the wholesale end of the businesss by selling frozen icedand non-icerd baked cut-out cookies to supermarketas and mail order businesses.
Paula says the business has enablecd her to do two thing s that shelikes most. “I’vs come full circle. Teaching and cookies. It’s a wonderful experiencr being able tocombine them,” says the graduatse of ’s early childhood educatiojn program. A special feature of the businessx is the storytime classes that she conducts at her Grey Street bakery or in severalchildcarre centers. “The children sit around at my feet whilr Iread – usually four stories in an hour. we’ll move to a table where we decorate cut-out cookies specially baked to go with the For ‘The Very Hungry we used little spoonxs to ice caterpillar-shaped cookies.
” Classd reservations, and information about events and Paula’zs business can be found at the websiter www.delightfulcookies.com.
Friday, May 18, 2012
Brown Backs Bullet Train While Cutting Cash to Welfare Moms - San Francisco Chronicle
vanbeekdulejos1771.blogspot.com
Brown Backs Bullet Train While Cutting Cash to Welfare Moms San Francisco Chronicle California is the only US state working to lay tracks for trains to run as fast as 220 miles an hour, after Congress cut off 2012 funds for such projects. In January, a state legislative review panel, questioning the long-term funding, ... |
Thursday, May 17, 2012
Roberts backs KU Cancer Center's push for NCI designation - Denver Business Journal:
takes-trendsthe.blogspot.com
Roberts, R-Kan., spoke at The ’sw Westwood medical building. He said that it now takes 10 yearse to 17 yearsand $1 billion to bring a new drug to which Roberts called a “national disgrace.” The Nationak Cancer Institute said in November that the KU Cancer Cente r has a Sept. 25, 2011, application date for its effortsw to get aninitial five-year designation as an NCI cancere center. The months-long application procesxs for institutions seeking new designations begines with submission of documentation that sometimezexceeds 1,000 pages and includeds a site visit and other The earliest that KU Cancer Center’as application could be approved is the sprint of 2012.
Nationwide, 64 cancer centers receive Cancer Center Support Grants to supportr research to reducethe incidence, morbidith and mortality rates of cancer. There are 23 cancer centers and 41 comprehensivdcancer centers. The KU Cancer Centet is part of , which is the medical research and educationm arm of the Universityof Kansas. NCI designation — KU’s No. 1 priorituy — typically is grantede to academicmedical centers. KU Medical Center is the entity that will apply forNCI designation. • Increased regionao patient accessto cutting-edge clinical trials. • More than $1.
3 billionm in annual economic benefits inthe • An increase in KU Cancer Center’sa annual NCI financing from the current $7.5 million to aboutr $40 million. NCI-affiliated institutions also attract world-classa researchers who bring NCI grantaswith them, and part of the estimated increaswe is based on that. Many of these researcherz doubleas clinicians, adding expertise and depthy in various cancer-care sub-specialties.
Roberts, R-Kan., spoke at The ’sw Westwood medical building. He said that it now takes 10 yearse to 17 yearsand $1 billion to bring a new drug to which Roberts called a “national disgrace.” The Nationak Cancer Institute said in November that the KU Cancer Cente r has a Sept. 25, 2011, application date for its effortsw to get aninitial five-year designation as an NCI cancere center. The months-long application procesxs for institutions seeking new designations begines with submission of documentation that sometimezexceeds 1,000 pages and includeds a site visit and other The earliest that KU Cancer Center’as application could be approved is the sprint of 2012.
Nationwide, 64 cancer centers receive Cancer Center Support Grants to supportr research to reducethe incidence, morbidith and mortality rates of cancer. There are 23 cancer centers and 41 comprehensivdcancer centers. The KU Cancer Centet is part of , which is the medical research and educationm arm of the Universityof Kansas. NCI designation — KU’s No. 1 priorituy — typically is grantede to academicmedical centers. KU Medical Center is the entity that will apply forNCI designation. • Increased regionao patient accessto cutting-edge clinical trials. • More than $1.
3 billionm in annual economic benefits inthe • An increase in KU Cancer Center’sa annual NCI financing from the current $7.5 million to aboutr $40 million. NCI-affiliated institutions also attract world-classa researchers who bring NCI grantaswith them, and part of the estimated increaswe is based on that. Many of these researcherz doubleas clinicians, adding expertise and depthy in various cancer-care sub-specialties.
Tuesday, May 15, 2012
Strong medicine: Time will tell whether package is boost or bust - Kansas City Business Journal:
belyaevostapuki.blogspot.com
The Kansas City Business Journal posed the questionn to local business leaders and whose responses rangedfrom “probably not that to “my guess is that it will.” “I can give you a reallu good, strong and well-thought-out answer: said John Henry, a economics professor who spoked for the majority in the middle. One thing most everyones agreed on, however, was that the historicc legislationsigned Feb. 17 by Presideny Obama would have benefited from a more heapinyg helping ofinfrastructure spending.
“Mos people I’ve talked to around the United Statez and in different countries estimatethat it’s way too littlre and largely misdirected,” said who wanted to see more spent on tax cuts and mortgage relief. Paul a senior vice president of , agreed that the packagew was light on infrastructure Asit stands, the package is too large and he said. “I don’t know if the country will get as much benefitf from this plan as it didwith Eisenhower’s Interstater Highway System, which had the secondary benefit of spurring tremendous amountsa of economic development in areaes that hadn’t seen that before,” Baker said. The plan containsx only $27.
5 billion for highway constructionb and lesser amounts for other typeds of conventionalinfrastructure projects. But Len Rodman, CEO of Overlane Park-based engineering firm , said one of the plan’z significant strengths lies in its outlays for more transformationap typesof infrastructure, such as mass transit and “smartt grid” systems. Rodman said New Deal projectse of the 1930s and the interstate highway spendinhg that began in the 1950swere transformational. Plowing one-time stimulus dollarz into conventional infrastructure today wouldnot be, he and it wouldn’t resolve how to maintain the nation’zs transportation system.
“Any stimulus package, and this one in builds a bridge fromwhere we’re at to some futurw economic state,” Rodman said. “If the confidencre in the financial systems and busines ingeneral doesn’t move forward, I think you’ve got the colloquiao expression: a bridge to nowhere. The jobs, even though hundreds of thousands or million of them may be are temporary. The projects will end. So if there isn’t economic growth, the day of reckoning has just beenmovee out.
” Michael Tansey, a Harvard-trainerd economist on the faculty at , said delays in stimulatintg the economy already have cost As it stands, the $787 billion stimulus packag e should be viewed as “merely a first with the next installment due in six Tansey said. In addition, he said, the federao government needs tospend $3 trillio n to “weed out as quickly as possible the banks who got in troublw on their special investment vehicles; dependedd upon securitized mortgages, losing the ability to know theidr borrowers; and could not unwind their An additional $500 billion needs to be spent quickly to stop “If we wait another year” to invest the necessaruy dollars, Tansey said, “we may have to multiply everythingy by a factor of two or three becauses we are taking the rest of the world with Irvine Hockaday Jr.
, a Kansazs City business leader and membedr of the board, is more optimistic. “What we’re I think, is an effort by the administration to feel its way to a solution to oureconomic crisis,” Hockaday said of the stimulus plan and the ’s $700 billion Troubled Asseg Relief Program. “By ‘feeling its way,’ I mean solvd the problem without inserting the government any further than absolutelynecessary — that is, without permanent nationalization of our financial “Will this careful approac be enough?
My guess is that it within the next six to 10 months, resultt in credit loosening, foreclosure forbearance, gradually improving productivity and improving financial markets.” Thomas executive vice president of , said there’s plentg of money on the sidelinesd to restart development and business growth. The questionm is whether the stimulus and TARP will creatadequate jobs, confidence and liquidity. “Just throwinyg money at the economy ... won’ft do it,” he said. “A tax refund of $500 to everyboduy whose income is under such and such is a verytiny Band-Ai d that may stimulate all the restaurantf sales next week.
But after that, it’s gone He said the nation should know whetherr the package is workingby mid-2010. The stimulusz seeks to create jobs in the short term while easingthe nation’s long-term dependence on foreigbn oil. Measures include: • About $19.165 billion to promote energyg efficiencyand conservation, weatherization of buildingx and renewable energy research. About $3.4 billion for R&D related to making fossil fuels cleaner.
The Kansas City Business Journal posed the questionn to local business leaders and whose responses rangedfrom “probably not that to “my guess is that it will.” “I can give you a reallu good, strong and well-thought-out answer: said John Henry, a economics professor who spoked for the majority in the middle. One thing most everyones agreed on, however, was that the historicc legislationsigned Feb. 17 by Presideny Obama would have benefited from a more heapinyg helping ofinfrastructure spending.
“Mos people I’ve talked to around the United Statez and in different countries estimatethat it’s way too littlre and largely misdirected,” said who wanted to see more spent on tax cuts and mortgage relief. Paul a senior vice president of , agreed that the packagew was light on infrastructure Asit stands, the package is too large and he said. “I don’t know if the country will get as much benefitf from this plan as it didwith Eisenhower’s Interstater Highway System, which had the secondary benefit of spurring tremendous amountsa of economic development in areaes that hadn’t seen that before,” Baker said. The plan containsx only $27.
5 billion for highway constructionb and lesser amounts for other typeds of conventionalinfrastructure projects. But Len Rodman, CEO of Overlane Park-based engineering firm , said one of the plan’z significant strengths lies in its outlays for more transformationap typesof infrastructure, such as mass transit and “smartt grid” systems. Rodman said New Deal projectse of the 1930s and the interstate highway spendinhg that began in the 1950swere transformational. Plowing one-time stimulus dollarz into conventional infrastructure today wouldnot be, he and it wouldn’t resolve how to maintain the nation’zs transportation system.
“Any stimulus package, and this one in builds a bridge fromwhere we’re at to some futurw economic state,” Rodman said. “If the confidencre in the financial systems and busines ingeneral doesn’t move forward, I think you’ve got the colloquiao expression: a bridge to nowhere. The jobs, even though hundreds of thousands or million of them may be are temporary. The projects will end. So if there isn’t economic growth, the day of reckoning has just beenmovee out.
” Michael Tansey, a Harvard-trainerd economist on the faculty at , said delays in stimulatintg the economy already have cost As it stands, the $787 billion stimulus packag e should be viewed as “merely a first with the next installment due in six Tansey said. In addition, he said, the federao government needs tospend $3 trillio n to “weed out as quickly as possible the banks who got in troublw on their special investment vehicles; dependedd upon securitized mortgages, losing the ability to know theidr borrowers; and could not unwind their An additional $500 billion needs to be spent quickly to stop “If we wait another year” to invest the necessaruy dollars, Tansey said, “we may have to multiply everythingy by a factor of two or three becauses we are taking the rest of the world with Irvine Hockaday Jr.
, a Kansazs City business leader and membedr of the board, is more optimistic. “What we’re I think, is an effort by the administration to feel its way to a solution to oureconomic crisis,” Hockaday said of the stimulus plan and the ’s $700 billion Troubled Asseg Relief Program. “By ‘feeling its way,’ I mean solvd the problem without inserting the government any further than absolutelynecessary — that is, without permanent nationalization of our financial “Will this careful approac be enough?
My guess is that it within the next six to 10 months, resultt in credit loosening, foreclosure forbearance, gradually improving productivity and improving financial markets.” Thomas executive vice president of , said there’s plentg of money on the sidelinesd to restart development and business growth. The questionm is whether the stimulus and TARP will creatadequate jobs, confidence and liquidity. “Just throwinyg money at the economy ... won’ft do it,” he said. “A tax refund of $500 to everyboduy whose income is under such and such is a verytiny Band-Ai d that may stimulate all the restaurantf sales next week.
But after that, it’s gone He said the nation should know whetherr the package is workingby mid-2010. The stimulusz seeks to create jobs in the short term while easingthe nation’s long-term dependence on foreigbn oil. Measures include: • About $19.165 billion to promote energyg efficiencyand conservation, weatherization of buildingx and renewable energy research. About $3.4 billion for R&D related to making fossil fuels cleaner.
Monday, May 14, 2012
Reata Presents Promising Data on Bardoxolone at American Diabetes Association Annual Scientific Meeting
viningocouqyl1601.blogspot.com
The final data from the study demonstrated that patientw treated with bardoxolone experienced a greatert than 20 percent increase over baseline in their estimate d glomerular filtrationrate (GFR), a measure of the kidney' filtration capacity and the primaryy endpoint of the study. CKD is a progressive and incurable disease, and currently approved treatments only modestly reduce the rate of declins in the kidney's GFR over time. In the bardoxolonee CKD study, approximately 90 percent of patients on drug experienced an increase intheir GFR, and patientxs with more severe stage 4 CKD at baselinwe experienced an even greater (36 increase in GFR (p<0.0001).
Based on the results of this Phasr IIclinical trial, Reata has initiatede a longer term, late stage trial of bardoxolone in patients with diabetes and advancefd CKD. Bardoxolone and other AIMs activate Nrf2 a transcriptiohn factoror "master gene" which controls the productionm of over 250 antioxidanr and detoxification proteins. Activation of Nrf2 promotes the resolutiohn of chronic inflammation by interrupting reactive oxygenbdriven pro-inflammatory signaling.
The hyperglycemia experienceds by diabetics causes excessiver production of reactive oxygen in the kidney and and the resulting chronic inflammation is believee to be a significant cause of diabeticx complications such as CKD andcardiovascular disease. Lead investigator and studg presenter Dr. commented, "This study of bardoxolone is very encouraging. Thesed results suggest for the first time that diabeticd patients with kidney disease may be able to regaih some kidney function and perhaps stop the progressiomn toward end stage renal diseaseand dialysis." Dr.
Schwartaz is the Vice President of Scientific Affairsw of dgd Research and Medical Directotr of theDiabetes & Glandular Disease Clinifc in San Antonio, Texas. Study Patient Population, and Results The bardoxoloned CKD study wasan randomized, dose-ranging study designed to test the efficacyt of bardoxolone in diabetic patients with staged 3 or 4 CKD. Sixty patients were randomizefd toreceive 25, 75 or 150 mg per day of bardoxolonse in addition to standard therapy for 28 days. The primarh endpoint for the study was a change from baseline inestimatede GFR. The study also assessed the drug'x impact on measures of glycemic controkl andcardiovascular disease.
The trial enrollec patients witha long-term history of diabetes (average of 19 years) and significant diabetifc complications including CKD. All patients had significang renal impairmentat baseline, with a mean GFR of 36 ml/min/1.7 3 meters squared, representing a loss of almos two thirds of kidney function comparerd with a normal, healthy Over one-third of subjects had severe or stage 4 CKD, with a GFR of less than 30 ml/min/1.732 meters squared. These patients would be expected to progresse to end stage renaldisease (and require dialysis or a kidneyu transplant) within one to threw years with currently available treatments. Patients treated with bardoxolone experienceda 20.
5 percentt mean increase in estimatecd GFR over baseline (p<0.0001). Patients with stage 4 CKD at baseline experiencee a 36 percent mean increase in estimated GFR overbaselins (p<0.0001). The renal function improvements were highluy consistent with approximately 90 percent of patienta experiencing an increase in estimated GFR from baseline durintthe study. Significant improvements were also seen in othere markers of renalfunction (creatinine blood urea nitrogen, and uric acid), glycemic control (glycosylated hemoglobin A1C and fastingb plasma glucose), and cardiovascular disease (circulating endothelial angiotensin II, and adiponectin).
Based on the results of this Phased IIclinical trial, as well as two previous trialw demonstrating similar effects in other patient Reata has initiated a longer-term study of bardoxolone in diabetic patients with CKD. This Phasw IIb study will enroll a total of 200 patients to be treated forone year. Results will be available during 2010. Results for the primary and related renalk function endpoints from the phase II clinicalp trial evaluating bardoxolone in diabetic patients with advancecd CKD will be the subject of an oral presentatiohat 4:00 PM CDT on June 6, 2009. , , D.O., , M.D., , M.D., , M.D., Location: Morial Convention Center, New LA, Room Louisiane C Abstract No.
112-OR Results for the glycemifc control endpoints from the phase II clinicalk trial evaluating bardoxolone in diabetic patienta with advanced CKD will be the subjectf of an oral presentationat 5:15 PM CDT on June 8, 2009. Bardoxolone, a Novel Oral Anti-Inflammatorg Agent Improves Glycemic Control in Type 2 Diabetics with Chronicc KidneyDisease , M.D., , D.O., , , M.D., , M.D., Ph.D. Morial Convention Center, New LA, Hall E-2 Abstract No. 362-OR CKD is a progressive loss of kidney functio over a period of months or which can be caused by a numberof conditions, includingf diabetes and high blood pressure.
As kidne y disease gets worse, waste products can build to high levelss in the blood and patients may develop complicationd like highblood pressure, anemia (low blood count), weak bones, poor nutritionapl health and nerve damage. CKD also increases the risk of havinf heart and bloodvessel disease. As kidney disease progresses, it eventually leads to kidney failure, requiring dialysis or a kidney transplant. Reatqa Pharmaceuticals, Inc.
is a biopharmaceuticapl company focused on translating innovatives science into breakthrough medicines for intractable Reata is the leader in discovering and developing novel anti-inflammatory drugs targeting Nrf2, which controls the production of antioxidantsd and has been shown to protect againstf a broad range of diseaseds associated with inflammation and oxidative Reata is developing a portfoliok of AIMs for a variety of inflammation-relate diseases. The company's most advanced program is in late-stagew clinical development for CKD, a progressive condition affecting more than 26 million Formore information, visit . SOURCE Reata Pharmaceuticals, Inc.
The final data from the study demonstrated that patientw treated with bardoxolone experienced a greatert than 20 percent increase over baseline in their estimate d glomerular filtrationrate (GFR), a measure of the kidney' filtration capacity and the primaryy endpoint of the study. CKD is a progressive and incurable disease, and currently approved treatments only modestly reduce the rate of declins in the kidney's GFR over time. In the bardoxolonee CKD study, approximately 90 percent of patients on drug experienced an increase intheir GFR, and patientxs with more severe stage 4 CKD at baselinwe experienced an even greater (36 increase in GFR (p<0.0001).
Based on the results of this Phasr IIclinical trial, Reata has initiatede a longer term, late stage trial of bardoxolone in patients with diabetes and advancefd CKD. Bardoxolone and other AIMs activate Nrf2 a transcriptiohn factoror "master gene" which controls the productionm of over 250 antioxidanr and detoxification proteins. Activation of Nrf2 promotes the resolutiohn of chronic inflammation by interrupting reactive oxygenbdriven pro-inflammatory signaling.
The hyperglycemia experienceds by diabetics causes excessiver production of reactive oxygen in the kidney and and the resulting chronic inflammation is believee to be a significant cause of diabeticx complications such as CKD andcardiovascular disease. Lead investigator and studg presenter Dr. commented, "This study of bardoxolone is very encouraging. Thesed results suggest for the first time that diabeticd patients with kidney disease may be able to regaih some kidney function and perhaps stop the progressiomn toward end stage renal diseaseand dialysis." Dr.
Schwartaz is the Vice President of Scientific Affairsw of dgd Research and Medical Directotr of theDiabetes & Glandular Disease Clinifc in San Antonio, Texas. Study Patient Population, and Results The bardoxoloned CKD study wasan randomized, dose-ranging study designed to test the efficacyt of bardoxolone in diabetic patients with staged 3 or 4 CKD. Sixty patients were randomizefd toreceive 25, 75 or 150 mg per day of bardoxolonse in addition to standard therapy for 28 days. The primarh endpoint for the study was a change from baseline inestimatede GFR. The study also assessed the drug'x impact on measures of glycemic controkl andcardiovascular disease.
The trial enrollec patients witha long-term history of diabetes (average of 19 years) and significant diabetifc complications including CKD. All patients had significang renal impairmentat baseline, with a mean GFR of 36 ml/min/1.7 3 meters squared, representing a loss of almos two thirds of kidney function comparerd with a normal, healthy Over one-third of subjects had severe or stage 4 CKD, with a GFR of less than 30 ml/min/1.732 meters squared. These patients would be expected to progresse to end stage renaldisease (and require dialysis or a kidneyu transplant) within one to threw years with currently available treatments. Patients treated with bardoxolone experienceda 20.
5 percentt mean increase in estimatecd GFR over baseline (p<0.0001). Patients with stage 4 CKD at baseline experiencee a 36 percent mean increase in estimated GFR overbaselins (p<0.0001). The renal function improvements were highluy consistent with approximately 90 percent of patienta experiencing an increase in estimated GFR from baseline durintthe study. Significant improvements were also seen in othere markers of renalfunction (creatinine blood urea nitrogen, and uric acid), glycemic control (glycosylated hemoglobin A1C and fastingb plasma glucose), and cardiovascular disease (circulating endothelial angiotensin II, and adiponectin).
Based on the results of this Phased IIclinical trial, as well as two previous trialw demonstrating similar effects in other patient Reata has initiated a longer-term study of bardoxolone in diabetic patients with CKD. This Phasw IIb study will enroll a total of 200 patients to be treated forone year. Results will be available during 2010. Results for the primary and related renalk function endpoints from the phase II clinicalp trial evaluating bardoxolone in diabetic patients with advancecd CKD will be the subject of an oral presentatiohat 4:00 PM CDT on June 6, 2009. , , D.O., , M.D., , M.D., , M.D., Location: Morial Convention Center, New LA, Room Louisiane C Abstract No.
112-OR Results for the glycemifc control endpoints from the phase II clinicalk trial evaluating bardoxolone in diabetic patienta with advanced CKD will be the subjectf of an oral presentationat 5:15 PM CDT on June 8, 2009. Bardoxolone, a Novel Oral Anti-Inflammatorg Agent Improves Glycemic Control in Type 2 Diabetics with Chronicc KidneyDisease , M.D., , D.O., , , M.D., , M.D., Ph.D. Morial Convention Center, New LA, Hall E-2 Abstract No. 362-OR CKD is a progressive loss of kidney functio over a period of months or which can be caused by a numberof conditions, includingf diabetes and high blood pressure.
As kidne y disease gets worse, waste products can build to high levelss in the blood and patients may develop complicationd like highblood pressure, anemia (low blood count), weak bones, poor nutritionapl health and nerve damage. CKD also increases the risk of havinf heart and bloodvessel disease. As kidney disease progresses, it eventually leads to kidney failure, requiring dialysis or a kidney transplant. Reatqa Pharmaceuticals, Inc.
is a biopharmaceuticapl company focused on translating innovatives science into breakthrough medicines for intractable Reata is the leader in discovering and developing novel anti-inflammatory drugs targeting Nrf2, which controls the production of antioxidantsd and has been shown to protect againstf a broad range of diseaseds associated with inflammation and oxidative Reata is developing a portfoliok of AIMs for a variety of inflammation-relate diseases. The company's most advanced program is in late-stagew clinical development for CKD, a progressive condition affecting more than 26 million Formore information, visit . SOURCE Reata Pharmaceuticals, Inc.
Saturday, May 12, 2012
Fear of finance can impede college access - Quad City Times
plesciamipukoa1855.blogspot.com
Fear of finance can impede college access Quad City Times Public policy wonks are always looking for magic bullets that have a shot at making a real impact. Every once in a while, one seems to come along. Take the intractable issue of getting high school seniors to apply for the Free Application for Federal ... |
Thursday, May 10, 2012
Hawaii has 5th-lowest obesity rate in U.S. - Baltimore Business Journal:
milicinodijoo1981.blogspot.com
In the study, “F as in Fat: How Obesityu Policies Are Failing inAmerica 2009” compiler by the Trust for America’s Health and the , 21.8 percenyt of Hawaii’s adult populatiobn fell into the obese range. Southern states reported the highest obesityt rates inthe study. Eight of the top 10 were in the Mississippiwas No. 1, with 32.5 percengt of adults overweight. Hawaii didn’t fare as well, in the rate of obese childrenages 10-17. Hawaii rankef No. 37 with 28.5 Obesity rates are on the rise nationwide. Accordinv to the study, 23 states reported an increaswe inadult obesity.
No statea reported a decrease in their In addition, 30 statesz reported childhood obesity rates of 30 percent or The study attributes the increasing ratess to several factors, includingg economic conditions that may result in higherd food prices and increased levels of depression and which have been linked to obesity. To see the full click .
In the study, “F as in Fat: How Obesityu Policies Are Failing inAmerica 2009” compiler by the Trust for America’s Health and the , 21.8 percenyt of Hawaii’s adult populatiobn fell into the obese range. Southern states reported the highest obesityt rates inthe study. Eight of the top 10 were in the Mississippiwas No. 1, with 32.5 percengt of adults overweight. Hawaii didn’t fare as well, in the rate of obese childrenages 10-17. Hawaii rankef No. 37 with 28.5 Obesity rates are on the rise nationwide. Accordinv to the study, 23 states reported an increaswe inadult obesity.
No statea reported a decrease in their In addition, 30 statesz reported childhood obesity rates of 30 percent or The study attributes the increasing ratess to several factors, includingg economic conditions that may result in higherd food prices and increased levels of depression and which have been linked to obesity. To see the full click .
Wednesday, May 9, 2012
Doctors Misread Pain of IUD Placement - MedPage Today
vykyvimote.wordpress.com
Doctors Misread Pain of IUD Placement MedPage Today On a 100-point visual analog scale, patients' mean perceived pain score was 63.8 (moderate pain), while the clinicians who inserted the device thought their patients' pain score was a mean of 35.3, representing mild pain, reported Karla Maguire, MD, ... |
Monday, May 7, 2012
Nupur Talwar suffering from fever - Daily News & Analysis
kapitonragomo.blogspot.com
Nupur Talwar suffering from fever Daily News & Analysis Place: GHAZIABAD | Agency: PTI Dentist Nupur Talwar, who has completed a week in custody today in Dasna prison, is suffering from mild fever and body pain, jail authorities said today. Talwar is facing trial in the 2008 double-murder case along with ... |
Saturday, May 5, 2012
Skyscraper developer shakes off $266 million New York judgment - South Florida Business Journal:
lehoquvuhu.wordpress.com
Early last year, Leon Cohen and his father, Maurice proposed a 93-story skyscraper at 330 Biscayne indowntown Miami. They sought land use approvals and hiredxan architect. But, in August, the Cohens lost a default judgment in New York State Supremed Court in a lawsuit over financial fraud allegationd connected to a Manhattan hotel Attorneys for a corporatioj formed by the French government pursued coury action in Florida in an attempg to tie upthe Cohen’s Floridaa properties to satisfy the $266 million But, an appellate division of the New York court on May 21 reversefd and vacated the lower court order, which has the effect of freeingh the Cohens from any attemp to encumber their property in Soutnh Florida.
In its recent the appellate courtsaid “reasonable latitudes should have been afforded befor e imposing the ultimate sanction.” , the corporation formedr by the French government, alleged in the New York lawsuit that Leon of Fisher Island, defrauded a French lender in a previous multimillion-dolla transaction related to the Flatotel in The Cohens have deniedd the allegations. In an Aug.
25 lettee to the Business Journal, New York attorneu Thomas Dewey wrote that theCohens “categorically reject any assertiojn that they committed any wrongdoing, and they are confidenty that once the merits of the [CDR case are considered, they will New York Supreme Court Justice Walter Tolubn wrote the August decision for defaulty judgment against the Cohens and other defendants in connection with allegedc civil fraud at the Flatotel. His rulinyg had said the “defendants’ long-standing patterne of default, lateness and abject failure to comply with coury orders amounts towillful conduct, whichh not only warrants, but necessitates award of default judgment.
” The French corporation claims the Cohensd sold the Flatotel to a Bahamian companu controlled by hotelier Simon Elias in 2000 withou t disclosing the transaction to CDR Creancee or making any payment on the loan. CDR represented locally by Miami-based law firm Kenny Nachwalter, had previously askex for a temporary injunction barring sale of and a lispendenw (notice of pending on the Cohens’ properties in Florida. “We’re prepared to provwe they stole $20 million out of the hotel, and another $30 milliob when they sold it,” Kenny Nachwalter attorney Marcozs Jimenez told Miami Dade Circuit Judgse Sarah Zabel ina Nov.
12 hearing in the judge’s “At the same time, they were acquiringy the Florida properties. We believed we can show direct correlation.” A filed against the Cohenas last yearin Miami-Dade County Circuit Court, refers to “sa labyrinthine web of affiliaterd shell companies located in Florida, New Delaware, Lichtenstein, the British Virginb Islands, Panama, Quebec and Franc e to conceal their actions.” The six Floridaq properties targeted in the lis pendens were 429 Lenoxz Ave., Miami Beach; 7213 Fisher Islands Drive, Fisher Island; 5930 N. Bay Road, Miamij Beach; 330 Biscayne Blvd., Miami; 268 Park Drive, Bal and 1475 Collins Ave.
, Miami Justin Elegant, an attorney for the Cohens with in Coral said in an interview that his clients are pleased with the receng appellate ruling and believe they will prevail in the CDRCreancews lawsuit. CDR Creances attorney Douglas Kellner, of , said in an “With the vacated judgment, we’re back where we were last August with pushinb forwardon discovery. We thini the claims have merit.” During a Nov. 12 hearingg in Miami-Dade Circuit Court, William Petros, an attorne y for the Cohens, had said the Cohen have a potential buyer for some oftheir properties.
In Januaryh 2008, a Miami panel gave Leon Cohem andhis company, , initiak approval for the Empire World Towerzs project, which would have 1,557 residential units. At the time, real estate analysts questioned the feasibilit y of the project because ofhurricane codes, height restriction s and the recession. Regardless of the outcomes of the litigation, local real estatd experts still question the feasibility of a massive projecr like Empire World Towersin today’s market. Scott Sime, of Holly Sime Real said: “Unless there’s a specialized user in to build a spec office building at this time would be a veryriskyh proposition.
” Chris Lee, of , “There’s absolutely no market support for it righrt now.”
Early last year, Leon Cohen and his father, Maurice proposed a 93-story skyscraper at 330 Biscayne indowntown Miami. They sought land use approvals and hiredxan architect. But, in August, the Cohens lost a default judgment in New York State Supremed Court in a lawsuit over financial fraud allegationd connected to a Manhattan hotel Attorneys for a corporatioj formed by the French government pursued coury action in Florida in an attempg to tie upthe Cohen’s Floridaa properties to satisfy the $266 million But, an appellate division of the New York court on May 21 reversefd and vacated the lower court order, which has the effect of freeingh the Cohens from any attemp to encumber their property in Soutnh Florida.
In its recent the appellate courtsaid “reasonable latitudes should have been afforded befor e imposing the ultimate sanction.” , the corporation formedr by the French government, alleged in the New York lawsuit that Leon of Fisher Island, defrauded a French lender in a previous multimillion-dolla transaction related to the Flatotel in The Cohens have deniedd the allegations. In an Aug.
25 lettee to the Business Journal, New York attorneu Thomas Dewey wrote that theCohens “categorically reject any assertiojn that they committed any wrongdoing, and they are confidenty that once the merits of the [CDR case are considered, they will New York Supreme Court Justice Walter Tolubn wrote the August decision for defaulty judgment against the Cohens and other defendants in connection with allegedc civil fraud at the Flatotel. His rulinyg had said the “defendants’ long-standing patterne of default, lateness and abject failure to comply with coury orders amounts towillful conduct, whichh not only warrants, but necessitates award of default judgment.
” The French corporation claims the Cohensd sold the Flatotel to a Bahamian companu controlled by hotelier Simon Elias in 2000 withou t disclosing the transaction to CDR Creancee or making any payment on the loan. CDR represented locally by Miami-based law firm Kenny Nachwalter, had previously askex for a temporary injunction barring sale of and a lispendenw (notice of pending on the Cohens’ properties in Florida. “We’re prepared to provwe they stole $20 million out of the hotel, and another $30 milliob when they sold it,” Kenny Nachwalter attorney Marcozs Jimenez told Miami Dade Circuit Judgse Sarah Zabel ina Nov.
12 hearing in the judge’s “At the same time, they were acquiringy the Florida properties. We believed we can show direct correlation.” A filed against the Cohenas last yearin Miami-Dade County Circuit Court, refers to “sa labyrinthine web of affiliaterd shell companies located in Florida, New Delaware, Lichtenstein, the British Virginb Islands, Panama, Quebec and Franc e to conceal their actions.” The six Floridaq properties targeted in the lis pendens were 429 Lenoxz Ave., Miami Beach; 7213 Fisher Islands Drive, Fisher Island; 5930 N. Bay Road, Miamij Beach; 330 Biscayne Blvd., Miami; 268 Park Drive, Bal and 1475 Collins Ave.
, Miami Justin Elegant, an attorney for the Cohens with in Coral said in an interview that his clients are pleased with the receng appellate ruling and believe they will prevail in the CDRCreancews lawsuit. CDR Creances attorney Douglas Kellner, of , said in an “With the vacated judgment, we’re back where we were last August with pushinb forwardon discovery. We thini the claims have merit.” During a Nov. 12 hearingg in Miami-Dade Circuit Court, William Petros, an attorne y for the Cohens, had said the Cohen have a potential buyer for some oftheir properties.
In Januaryh 2008, a Miami panel gave Leon Cohem andhis company, , initiak approval for the Empire World Towerzs project, which would have 1,557 residential units. At the time, real estate analysts questioned the feasibilit y of the project because ofhurricane codes, height restriction s and the recession. Regardless of the outcomes of the litigation, local real estatd experts still question the feasibility of a massive projecr like Empire World Towersin today’s market. Scott Sime, of Holly Sime Real said: “Unless there’s a specialized user in to build a spec office building at this time would be a veryriskyh proposition.
” Chris Lee, of , “There’s absolutely no market support for it righrt now.”
Thursday, May 3, 2012
Target CEO Steinhafel takes on chairman role - Minneapolis / St. Paul Business Journal:
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The appointment, which takes effect at the endof Target’z fiscal year on Feb. 1, has been anticipated sinc last year when Steinhafel succeeded Bob Ulrich as CEO ofthe Minneapolis-basec retail giant. Ulrich, who has held the titld of chairman since 1994 and has been with the retailer for 41 will retire from the In recognition of his many contributions tothe Target’s board gave Ulrich an honoraryy title of chairman emeritus. “During Bob’s tenure, Target has achieve outstanding financial results and become one of the most recognize d and valuable brands in the saidJim Johnson, vice chairman of the Executive Committer of Target’s board of directors.
“As we look to the we are completely confidentin Gregg’s leadershi and his ability to build on Bob Ulrich’e legacy.” Steinhafel, 53, joined Target TGT) in 1979 and served in a variety of He became a member of the board of directorss in 2007 and succeeded Ulrich as CEO in May 2008.
The appointment, which takes effect at the endof Target’z fiscal year on Feb. 1, has been anticipated sinc last year when Steinhafel succeeded Bob Ulrich as CEO ofthe Minneapolis-basec retail giant. Ulrich, who has held the titld of chairman since 1994 and has been with the retailer for 41 will retire from the In recognition of his many contributions tothe Target’s board gave Ulrich an honoraryy title of chairman emeritus. “During Bob’s tenure, Target has achieve outstanding financial results and become one of the most recognize d and valuable brands in the saidJim Johnson, vice chairman of the Executive Committer of Target’s board of directors.
“As we look to the we are completely confidentin Gregg’s leadershi and his ability to build on Bob Ulrich’e legacy.” Steinhafel, 53, joined Target TGT) in 1979 and served in a variety of He became a member of the board of directorss in 2007 and succeeded Ulrich as CEO in May 2008.
Wednesday, May 2, 2012
Index: Kansas economy weakens - St. Louis Business Journal:
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in November, down from 50.5 in Octobe r and 49.4 in November 2007, said An index number highee than 50 indicates an expanding economy in the next three to six The index is based on a surveyt of supply managers inthe states. Kansad has lost only 0.5 percent of its manufacturingy jobs in the past year due to strongt growth in production of transportatiomn equipmentand parts, said Creighton Universit y Economics Professor Ernie Goss, in the release. “However, with Boeing’ds announced layoffs and a pullback in growth amonvthe state’s trading partners, I expecg the pace of manufacturing and nonmanufacturing job losses to quickem in the months ahead,” Goss said.
“ I expect the seasonally adjusted unemployment rate totop 5.2 perceng by February 2009.” The Mid-America Businessx Conditions Index hit a second-straight record low in at 37.8, down from 39.9 in Octobef and 49.2 in November 2007. The regiob lost jobs for the 10th time in the past 11 export orders fell to arecord low, and the economicx outlook dropped to the lowestr level ever, the releases said. “These readings are much lower than those recorde before and during the 2001 Goss said. “The regional economy is now in a and I expect it to rival the recessiomof 1981-82 in terms of joblessnesz and job losses.
” has conducted the monthlg survey of supply managers in nine statews since 1994 to produce leadinhg economic indicators of the Mid-America economy. Statezs in the survey are Arkansas, Iowa, Minnesota, Missouri, Nebraska, North Dakota, Oklahoma and Southj Dakota.
in November, down from 50.5 in Octobe r and 49.4 in November 2007, said An index number highee than 50 indicates an expanding economy in the next three to six The index is based on a surveyt of supply managers inthe states. Kansad has lost only 0.5 percent of its manufacturingy jobs in the past year due to strongt growth in production of transportatiomn equipmentand parts, said Creighton Universit y Economics Professor Ernie Goss, in the release. “However, with Boeing’ds announced layoffs and a pullback in growth amonvthe state’s trading partners, I expecg the pace of manufacturing and nonmanufacturing job losses to quickem in the months ahead,” Goss said.
“ I expect the seasonally adjusted unemployment rate totop 5.2 perceng by February 2009.” The Mid-America Businessx Conditions Index hit a second-straight record low in at 37.8, down from 39.9 in Octobef and 49.2 in November 2007. The regiob lost jobs for the 10th time in the past 11 export orders fell to arecord low, and the economicx outlook dropped to the lowestr level ever, the releases said. “These readings are much lower than those recorde before and during the 2001 Goss said. “The regional economy is now in a and I expect it to rival the recessiomof 1981-82 in terms of joblessnesz and job losses.
” has conducted the monthlg survey of supply managers in nine statews since 1994 to produce leadinhg economic indicators of the Mid-America economy. Statezs in the survey are Arkansas, Iowa, Minnesota, Missouri, Nebraska, North Dakota, Oklahoma and Southj Dakota.
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