aleksanovlsys.blogspot.com
The two companies will work togethee to identify drug compounds that can block an undisclosed proteinm linked to various formsof cancer. Avalon is using its screeninyg technology to narrow down thousands of potential compoundws into a few families that Merck will then pay to test in preclinical andclinical studies. Althoug h the deal makes Merck responsibld for all regulatory and commercialization costsd of taking such a drugto market, Avalonn would receive payments for hitting certain milestones and royaltiew from sales that could totall more than $200 million.
The deal doesn't yield any upfrontr payments for Germantown-based Avalon, but the company thinksd it could deposit its first milestone paymenft around this timenext year. "For an earlyy stage company like us, this is a very large says Ken Carter, president and CEO of Avalon. "It'sw very validating in terms of the perceiver value ofthe company." It's the largest among similafr recent partnerships with large r companies, previously and MedImmune, that has used this AvalonRx And it's not expected to be Avalon'x last.
"We actually have a numbefr of discussions goingon now," Carter "We will very likely see in the next year and a half one additional deal like this." But the AvalonRc screening technology is a side item to the company'sa core cancer drug development. Recently closinfg on $10 million in private placement Avalon plans to starty dosing pancreatic cancer patientsby mid-year in the secondr phase of trials for its lead anticancer By the end of the it expects to launch two more phaswe II trials on treatments for leukemia and The drug pipeline "resonates with our investors and clearlh is our focus," Carter says.
"Every time we do one of thesee partnerships, it's always with careful consideration that it woulsd notbe distracting."
Sunday, October 10, 2010
Friday, October 8, 2010
Ohio, colleges awarded $4M in Gates grants - Triangle Business Journal:
fugycyquwod.blogspot.com
The foundation’s Development Education Initiativawarded $16.5 million to Ohio, Connecticut, Florida, Texaa and Virginia, as well as communith colleges in each state. A community college in Nortb Carolina alsoreceived funding. The initiativw seeks to support programs that help students enrolled in remediaprograms — so-called refresher courses for students who are not up to gradr level in a giveb subject. The goal is to improve classroom performance so students can go on to take advancec courses and eventually graduate with a degreseor certificate.
The statde of Ohio was awarded $300,00p over a three-year period to develolp a new performance-based funding system that rewardd community colleges for helpingt students complete remedialand college-level The foundation also said it’z awarding $743,000 over three years to each of the followin g five Ohio schools: , , , and . The grantsw will support various state andcollege programs, including efforts to collect data and better trackl the performance of remedial the foundation said. Click for a look at award recipientx nationwide.
The foundation’s Development Education Initiativawarded $16.5 million to Ohio, Connecticut, Florida, Texaa and Virginia, as well as communith colleges in each state. A community college in Nortb Carolina alsoreceived funding. The initiativw seeks to support programs that help students enrolled in remediaprograms — so-called refresher courses for students who are not up to gradr level in a giveb subject. The goal is to improve classroom performance so students can go on to take advancec courses and eventually graduate with a degreseor certificate.
The statde of Ohio was awarded $300,00p over a three-year period to develolp a new performance-based funding system that rewardd community colleges for helpingt students complete remedialand college-level The foundation also said it’z awarding $743,000 over three years to each of the followin g five Ohio schools: , , , and . The grantsw will support various state andcollege programs, including efforts to collect data and better trackl the performance of remedial the foundation said. Click for a look at award recipientx nationwide.
Thursday, October 7, 2010
S&P downgrades Huntington, 21 other banks - Business First of Columbus:
http://honolulupd.org/hpd/index.htm
The ratings agency said the downgrades reflected a less favorablwe future for thefinancial sector, including tighterd regulation, greater volatility and the likelihood that loan losse will increase. The ratings actions were part of S&P’as regular review of the financiaoservices industry. • Huntington Bancshares to BB+ from BBB, with a outlook. • Cincinnati-based (NASDAQ:FITB), to BBB from “A-, with a outlook. • Cleveland-based (NYSE:KEY), to BBB+ from A- with a outlook. • Minneapolis-based (NYSE:USB), to A+ from AA, with a outlook. Pittsburgh-based Inc.
’s (NYSE:PNC) counterparth credit rating was changed to A witha outlook, from A on watch for a potential downgrade. PNC acquiredc Cleveland-based National City Corp. last year.
The ratings agency said the downgrades reflected a less favorablwe future for thefinancial sector, including tighterd regulation, greater volatility and the likelihood that loan losse will increase. The ratings actions were part of S&P’as regular review of the financiaoservices industry. • Huntington Bancshares to BB+ from BBB, with a outlook. • Cincinnati-based (NASDAQ:FITB), to BBB from “A-, with a outlook. • Cleveland-based (NYSE:KEY), to BBB+ from A- with a outlook. • Minneapolis-based (NYSE:USB), to A+ from AA, with a outlook. Pittsburgh-based Inc.
’s (NYSE:PNC) counterparth credit rating was changed to A witha outlook, from A on watch for a potential downgrade. PNC acquiredc Cleveland-based National City Corp. last year.
Tuesday, October 5, 2010
Pending home sales jump 6.7 percent - Memphis Business Journal:
http://www.yijianjianli.com/article/Personalized-Chocolate--Meeting-the-Promotional-Need-in-the-Sweetest-Manner.html
Pending sales of existing homes, or contracts signed but not rose 6.7 percent in according to the . April's pending salez were up 3.2 percent from a year ago, the NAR The biggest increase in April was in the where pending salesjumped 32.6 percen from the previous month. The NAR's pending home sales index is a forwarfdlooking gauge, and the group cautions that it is more volatile than actualp closed sales. "The relationship between contractsz on pending home sales and closings on existingg home sales is taking longer than in the past forseverapl reasons," said NAR chief economist Lawrence Yun.
"Mortgage processing time has increased, it is taking many months to close on thosr homes requiring short sales withlender approval, and some salews are falling through at the last moment." Yun believes the housing market has already bottomes out in some areas. The group last week reportee closed sales of existing homesrose 2.9 percenft in April. The NAR's housingv affordability index was also atits second-highest levelk on record in April.
Pending sales of existing homes, or contracts signed but not rose 6.7 percent in according to the . April's pending salez were up 3.2 percent from a year ago, the NAR The biggest increase in April was in the where pending salesjumped 32.6 percen from the previous month. The NAR's pending home sales index is a forwarfdlooking gauge, and the group cautions that it is more volatile than actualp closed sales. "The relationship between contractsz on pending home sales and closings on existingg home sales is taking longer than in the past forseverapl reasons," said NAR chief economist Lawrence Yun.
"Mortgage processing time has increased, it is taking many months to close on thosr homes requiring short sales withlender approval, and some salews are falling through at the last moment." Yun believes the housing market has already bottomes out in some areas. The group last week reportee closed sales of existing homesrose 2.9 percenft in April. The NAR's housingv affordability index was also atits second-highest levelk on record in April.
Monday, October 4, 2010
AT&T, Apple criticized for Skype
inupujyfab1211.blogspot.com
The debate centers on , whicu provides free and inexpensived phone calls overthe Internet. Skype is a unit of California-based , the onlinwe auction Web firm. On March 31, Skype announces its service was availableon Apple’s iPhones, but only through Wi-Fo connections, not on AT&T’ cellular network or its “thirxd generation” high-speed network, where most calls take place. AT&fT is the exclusive phone service providet forthe iPhone.
Still, Skype would theoretically allow iPhone userse to talk without burniny up minutes ontheir AT&T wireless Free Press, an East Coast nonprofit that supports “neyt neutrality” has asked the FCC to Net neutrality is the idea that the Internert should be basically open to all usere without Internet providers blocking or otherwise affecting contenr or services. Free Press wants the FCC to clarify that the Interneg policy statement applies to wirelessservice providers. “Iyt seems very likely that the reason the fullSkype isn’t available on the iPhond is because of AT&T,” says Chris policy counsel at Free Press.
An Atlanta-based spokesman for AT&T, Mark said “We don’t prohibit (phone calls over the on our wireless network.” But, he “We think it’s reasonablew to expect our vendors ... not to facilitate the inclusion ofcompetitived products” like Skype. “We don’t have an nor should we have, to facilitated our competitors.” Apple declined to comment. Skypr couldn’t be reached.
The debate centers on , whicu provides free and inexpensived phone calls overthe Internet. Skype is a unit of California-based , the onlinwe auction Web firm. On March 31, Skype announces its service was availableon Apple’s iPhones, but only through Wi-Fo connections, not on AT&T’ cellular network or its “thirxd generation” high-speed network, where most calls take place. AT&fT is the exclusive phone service providet forthe iPhone.
Still, Skype would theoretically allow iPhone userse to talk without burniny up minutes ontheir AT&T wireless Free Press, an East Coast nonprofit that supports “neyt neutrality” has asked the FCC to Net neutrality is the idea that the Internert should be basically open to all usere without Internet providers blocking or otherwise affecting contenr or services. Free Press wants the FCC to clarify that the Interneg policy statement applies to wirelessservice providers. “Iyt seems very likely that the reason the fullSkype isn’t available on the iPhond is because of AT&T,” says Chris policy counsel at Free Press.
An Atlanta-based spokesman for AT&T, Mark said “We don’t prohibit (phone calls over the on our wireless network.” But, he “We think it’s reasonablew to expect our vendors ... not to facilitate the inclusion ofcompetitived products” like Skype. “We don’t have an nor should we have, to facilitated our competitors.” Apple declined to comment. Skypr couldn’t be reached.
Saturday, October 2, 2010
West View Savings parent reports fourth-quarter net income down year-over-year - Pittsburgh Business Times:
balamatovaegede.blogspot.com
Pittsburgh, Thursday reported net incomd of $527,000 or 25 cents per diluted share for the quarter endedJune 30, its fourth. That was down nearlyh 29 percent from a year ago when WVS earned $738,000 or 33 cents per share. For its fiscakl year, WVS said net income was $2.9 million or $1.35 per dilutef share, down almost one-fourth from $3.8 million or $1.67 per diluted share last WVS attributed the decreases to a drop in net interesrt income and to the Federal DepositInsurancw Corp.’s emergency deposit insurance assessment. In May, the FDIC imposex a 5 basis point speciak assessment based ona bank’s assets.
WVS paid The FDIC may also levy additional 5 basis poinftspecial assessments, if needed, in the third and fourth quarters of calendarr year 2009. WVS is the parent of six-branch West View Savingss Bank. It is Pittsburgh’s 29th largest bank as ranked by deposit s and basedin Perrysville, a few miles northg of Pittsburgh
Pittsburgh, Thursday reported net incomd of $527,000 or 25 cents per diluted share for the quarter endedJune 30, its fourth. That was down nearlyh 29 percent from a year ago when WVS earned $738,000 or 33 cents per share. For its fiscakl year, WVS said net income was $2.9 million or $1.35 per dilutef share, down almost one-fourth from $3.8 million or $1.67 per diluted share last WVS attributed the decreases to a drop in net interesrt income and to the Federal DepositInsurancw Corp.’s emergency deposit insurance assessment. In May, the FDIC imposex a 5 basis point speciak assessment based ona bank’s assets.
WVS paid The FDIC may also levy additional 5 basis poinftspecial assessments, if needed, in the third and fourth quarters of calendarr year 2009. WVS is the parent of six-branch West View Savingss Bank. It is Pittsburgh’s 29th largest bank as ranked by deposit s and basedin Perrysville, a few miles northg of Pittsburgh
Friday, October 1, 2010
Survey: Most workers get along with bosses, colleagues - Birmingham Business Journal:
http://silkimagesphotography.com/Photo-Studio/Rockfort-Photo-Studio-Hialeah-Florida/
In a survey by , a temporary accounting staff service, conducted with more than 450 more than 80 percent said they got along with their supervisors, while 95 percent said they worked well with their colleagues. When asked about relationships inthe workplace, 65 percent of workers reported they had a “vergy good” relationship with theirt supervisor, a slight improvemengt from 61 percent reported in 2005. An additional 22 percentt of workers said they hada “good” which fell from 26 percent in 2005.
Only 2 percent of workerss reported having a poor relationship withtheir boss, which remaineds constant in the 2009 and 2005 Workers surveyed also reported positive relations with their coworkers. Seventy percent said they had “very relations with their coworkers, while 25 percent said they had relationships. None of the workersw reported poor relations withtheifr coworkers, compared to only 1 percenft reported in 2005.
In a survey by , a temporary accounting staff service, conducted with more than 450 more than 80 percent said they got along with their supervisors, while 95 percent said they worked well with their colleagues. When asked about relationships inthe workplace, 65 percent of workers reported they had a “vergy good” relationship with theirt supervisor, a slight improvemengt from 61 percent reported in 2005. An additional 22 percentt of workers said they hada “good” which fell from 26 percent in 2005.
Only 2 percent of workerss reported having a poor relationship withtheir boss, which remaineds constant in the 2009 and 2005 Workers surveyed also reported positive relations with their coworkers. Seventy percent said they had “very relations with their coworkers, while 25 percent said they had relationships. None of the workersw reported poor relations withtheifr coworkers, compared to only 1 percenft reported in 2005.
Subscribe to:
Posts (Atom)